Irg1 acod1
WebThis website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies. WebFeb 26, 2024 · Also known as CAD; Irg1 Summary Enables aconitate decarboxylase activity. Involved in several processes, including cellular response to cytokine stimulus; negative regulation of defense response; and negative regulation of signal transduction. Acts upstream of or within response to lipopolysaccharide. Located in mitochondrion.
Irg1 acod1
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WebListed are ELISA Kits for the detection of IRG1, an alias name of aconitate decarboxylase 1. The human protein, encoded by the gene ACOD1, is 481 amino acid residues long and has a mass of 52,628 daltons. It is a member of the PrpD family. This protein is reported to have a mitochondrial cellular localization. WebMar 15, 2024 · Download Citation IRG1/Itaconate induces metabolic reprogramming to suppress ER-positive breast cancer cell growth Most breast cancers are estrogen receptor (ER)-positive, targeted by ...
WebCitraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism Citraconate inhibits ACOD1 … WebFeb 10, 2024 · The immunoresponsive gene 1 (Irg-1), also known as Acod1, was first identified as a 2.3-kb cDNA from a murine macrophage cell line stimulated with lipopolysaccharide (LPS) .
WebApr 4, 2024 · Irg1 is a novel target of progesterone receptor in the pregnant uterus and also revealed that it is a critical regulator of the early events leading to implantation. Thus, our … WebDec 17, 2024 · ACOD1 (also known as IRG1) has emerged as a regulator of immunometabolism that operates by producing metabolite itaconate. Here, we report a key role of STING1 (also known as STING and TMEM173) in mediating ACOD1 expression in myeloid cells in response to toll-like receptor (TLR) signaling. The activation of STING1 …
WebDec 8, 2024 · ACOD1 aconitate decarboxylase 1. ACOD1. aconitate decarboxylase 1. Gene ID: 730249, updated on 22-Sep-2024. Gene type: protein coding. Also known as: CAD; IRG1. See all available tests in GTR for this gene. Go to complete Gene record for ACOD1. Go to Variation Viewer for ACOD1 variants. notre dame fighting irish football scoreboardWebSep 23, 2024 · Abstract cis -Aconitate decarboxylase (CAD, also known as ACOD1 or Irg1) converts cis -aconitate to itaconate and plays central roles in linking innate immunity with … notre dame fighting irish football on tvWebFeb 12, 2024 · Aconitate decarboxylase 1 (ACOD1, also known as immunoresponsive gene 1 [IRG1]) is a key regulator of immunometabolism during infection and inflammation.[20,21,22] It was first discovered in 1992 as a lipopolysaccharide (LPS)- inducible gene in murine macrophages.[] Later, metabolomics profiling analyses revealed that ACOD1 is … notre dame fighting irish football staffWebTurboCHO™ High Throughput Services as fast as 2 weeks; TurboCHO™ Protein Expression in Singapore as fast as 8 BDs; TurboCHO™ Protein Expression Upgraded; MonoRab™ Rabbit mAb; Anti-idiotype Antibody Services New!; Neoantigen Peptide Service New! CRISPR sgRNA Services how to shell hazelnutsWebApr 1, 2024 · ACOD1 in sterile inflammatory diseases. In addition to pathogen infections, inflammation can also be triggered by tissue damage and stress, leading to various … notre dame fighting irish football scoresWeb产品图片 产品编号 品牌 cas号 产品名称 分子式 购物车 how to shell green beansWebOct 29, 2024 · ACOD1 is a highly conserved gene that encodes an enzyme that catalyzes the decarboxylation of cis-aconitate to itaconic acid. Itaconic acid inhibits isocitrate lyase, a key enzyme of the glyoxylate shunt, a pathway essential for bacterial growth in macrophages ( Michelucci et al., 2013 ). Cloning and Expression notre dame fighting irish football post game