WebFeb 17, 2024 · Fosphenytoin: V d: 4.3 to 10.8 L; V d of fosphenytoin increases with dose and rate of administration (Fischer 2003) Metabolism. Fosphenytoin is rapidly converted via hydrolysis to phenytoin; phenytoin is metabolized in the liver and forms metabolites. Excretion. Phenytoin: Urine (as inactive metabolites) Time to Peak. Conversion to … Fosphenytoin is an anticonvulsant that is used to prevent or control seizures. Fosphenytoin is used short term or when other forms of phenytoincannot be given. Fosphenytoin may also be used for purposes not listed in this medication guide. See more Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies. See more Fosphenytoin is injected into a muscle or a vein by a healthcare provider. You will be watched closely for 10 to 20 minutes to make sure this … See more You should not use fosphenytoin if you are allergic to fosphenytoin or phenytoin, or if you have: 1. slow heartbeats; 2. Adams-Stokes syndrome (a … See more Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal. Overdose symptoms may include weakness, nausea, vomiting, … See more
fosphenytoin - UpToDate
WebFosphenytoin is a phenytoin prodrug that received an approvable letter from the Food and Drug Administration in February 1996. It was designed to overcome many of the shortcomings associated with parenteral phenytoin sodium. Specifically, fosphenytoin is a highly water-soluble, phosphate ester of ph … WebDibenzyl malonate; CAS Number: 15014-25-2; EC Number: 239-099-2; Linear Formula: CH2(CO2CH2C6H5)2; find Sigma-Aldrich-160407 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich florida production motor homes
Phenytoin: Dosage, Mechanism/Onset of Action, Half …
WebFosphenytoin C16H15N2O6P CID 56339 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … WebDibenzylamine. Molecular Formula CHN. Average mass 197.276 Da. Monoisotopic mass 197.120453 Da. ChemSpider ID 7373. WebDose conversion from fosphenytoin to phenytoin is a 1:1 ratio, with 1mg PE fosphenytoin = 1 mg phenytoin. Pediatrics: Loading dose: 18 to 20 mg/kg IV Maintenance dose: 2 to 3 mg/kg/ IV dose two times daily (4 to 6 mg/kg/day), though significantly higher dosing may be needed based upon levels. great west life tfsa