Chromomycin-a3
WebChromomycin A3 from Streptomyces griseus C57H82O26 CID 15953908 - structure, chemical names, physical and chemical properties, classification, patents, literature ... WebChromomycin A3 Revision Date 20-Feb-2024 www.alfa.com Revision Date 20-Feb-2024 Print Date 20-Feb-2024 Revision Summary SDS authoring systems update, replaces ChemGes SDS No. 7059-24-7. Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the
Chromomycin-a3
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WebJun 7, 2024 · The Chromomycin A3 (CMA3) and Acridine orange (AO) staining were performed to examine the sperm DNA fragmentation status. CCl4 treatment showed a significant decrease in antioxidant markers and sperm count, viability, normal morphology and motility as well as significantly increased the testicular oxidative stress markers, and … Chromomycin A3 (CMA3) or Toyomycin is an anthraquinone antibiotic glycoside produced by the fermentation of a certain strain of Streptomyces griseus (No. 7). See more In the presence of Mg ions, Chromomycin A3 binds reversibly to DNA, preferentially to contiguous G/C base pairs. When bound to DNA, Chromomycin A3 has a maximum excitation wavelength of 445 See more • in-vitro membrane-impermeant G/C-specific fluorescent DNA-binding dye. • in-vitro antibiotic of gram-positive bacteria, through inhibition of the incorporation of Pi in the RNA. • in-vitro anticancer drug that inhibits RNA synthesis. See more
WebChromomycin A3 from Streptomyces griseus is an antibiotic exhibiting anti-bacterial, anti-fungal and antitumor activities. [ 3] It serves as a fluorescent DNA stain. [ 4] It is useful … WebFeb 25, 1997 · The interaction of the two anticancer antibiotics, chromomycin A 3 and mithramycin, with the polynucleotides poly (dG-dC).poly (dC-dG), representative of B-DNA, and poly (dG)·poly (dC), representative of A-DNA, in the presence of Mg 2+ is studied by spectroscopic techniques such as absorbance, fluorescence, and dircular dichroism (CD).
WebApr 6, 2024 · Chromomycin A3 (CMA3, Figure 17.1) is an antibiotic glycoside produced by the fermentation of a certain strain of Streptomyces griseous. In the presence of bivalent … WebG-C specific intercalating agents [actinomycin D (AMD) and chromomycin A3 at 1 microM] also prevented ER disappearance; ethidium bromide (EB) and quinacrine were ineffective. AMD and CHX operated immediately after their addition to the medium indicating an inhibitory action on the synthesis of an RNA and/or a peptide with high turnover rate ...
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WebJan 14, 2024 · Description. Chromomycin A3 is an aureolic acid-type antitumor antibiotic. Chromomycin A3 forms dimeric complexes with divalent cations, such as Mg2+, which strongly binds to the GC rich sequence of DNA to inhibit DNA replication and transcription. Chromomycin A3 has a variety of utilities as a staining agent for human sperm … how does sugar cause fatty liver diseaseWebchromomycin A3 Acute Tox. 1; H300 <= 100 % For the full text of the H-Statements mentioned in this Section, see Section 16. SECTION 4: First aid measures 4.1 Description of first-aid measures General advice Show this material safety data sheet to the doctor in attendance. If inhaled After inhalation: fresh air. In case of skin contact photo tableclothWebIn-Person Course Schedule - Industrial Refrigeration …. 1 week ago Web Ends: Apr 21st 2024 5:00PM. Fee: $1,225.00. Register By: Apr 17th 2024 2:17PM. Collapse. This is a … how does sugar help plants and animalsWebChromomycin A₃ - CAS 7059-24-7 - Calbiochem Antitumor antibiotic that inhibits RNA synthesis. A cell-permeable fluorescent dye that can be used with Bisbenzimide H 33258 … photo table matsWebChromomycin A3, is used as a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye. Chromomycin A3 antagonizes enhanced DNA binding of … how does sugar turn into fatWebChromomycin A3 has a variety of utilities as a staining agent for human sperm chromatin, autophagy inducing agent, and apoptosis inhibitor. For research use only. We do not sell to patients. Chromomycin A3 … photo tabWeb(Hoechst 33258, Chromomycin A3). Highly purified fractions of chromosomes can then be isolated rapidly from the labeled chromosomes using the MoFlo High performance Cell Sorter. Chromosome preparation and staining. Block cells at metaphase using 0.1 µg/ml demecolcine for an optimized amount of time to maximize the percentage of mitotic cells photo tagging and organizing software